- Original Article
- Fas/FasL expression in the hippocampus of neonatal rat brains follwing hypoxic-ischemic injury
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Young Pyo Chang, Myeung Ju Kim, Young Il Lee, Ik Je Im, Jae Ju Cho, Jong-Wan Kim, Sung Moon Yeo
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Clin Exp Pediatr. 2006;49(2):198-202. Published online February 15, 2006
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Purpose : Fas is a cell surface receptor that transduces apoptotic death signals. Interaction of extracelluar domain of Fas with Fas ligand(FasL) triggers the apoptotic process in many diseases. We investigated the expression of Fas and FasL in the hippocampus of 7-day-old newborn rat brains following hypoxia-ischemia injury.
Methods : The 7-days-old newborn rats were exposed to 8 percent oxygen... |
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- Survival Rate in Very Low Birth Weight Infants
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Jae Ju Cho, Soon Bum Lee, Woo Sung Park, Young Pyo Chang
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Clin Exp Pediatr. 2004;47(5):505-509. Published online May 15, 2004
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Purpose : We observed changes in the outcome of very low birth weight infants(VLBWI) admitted to the neonatal intensive care unit(NICU) of Dankook University Hospital(DKUH) in the last six years.
Methods : The distribution of birth weight and gestational age, survival rate, neonatal complications, and causes of death for 228 VLBWI who had been admitted to DKUH from 1st January... |
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- Possible Neuroprotective Role of Exogenous Growth Hormone on Hypoxic-Ischemic Brain Injury in Neonatal Rats
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Young Pyo Chang, Mi Kyung Jung, Youn Hee Jee, Jae Ju Cho, Soon Bum Lee, Woo Sung Park, Jong-Wan Kim, Dong Hoon Shin
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Clin Exp Pediatr. 2004;47(11):1210-1215. Published online November 15, 2004
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Purpose : This study was performed to evaluate the possible neuroprotective effect of exogenous growth hormone on hypoxic-ischemic brain injury in neonatal rats.
Methods : After ligation of the right common carotid artery, seven-day old Sprague-Dawley rats(n= 75) were exposed to 8% oxygen for two hours. In a growth hormone(GH)-treated group(n=25), each animal was subcutanously injected by GH(50 mg/kg, Grotrpin ,... |
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- Case Report
- Congenital Pulmonary Vein Stenosis Manifested by Severe Cyanosis in Infancy
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Jae Ju Cho, Woo Sung Park, I-Seok Kang, Tae-Gook Jun, Mi-Jin Jung
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Clin Exp Pediatr. 2004;47(10):1114-1118. Published online October 15, 2004
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Congenital pulmonary vein stenosis(CPVS) with anatomically normal connection, a rare anomaly, usually leads to progressive pulmonary hypertension, cardiac failure in infancy, and death if untreated. Most are combined with other anomalies, particularly left to right shunt lesions. Very often, the detection of CPVS is overlooked on the initial cardiac echocardiogram, because it may be mild in its severity initially, but... |
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